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KMID : 0363220150530010053
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Korean Journal of Dermatology
2015 Volume.53 No. 1 p.53 ~ p.57
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Epidermotropic Metastatic Malignant Melanoma
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Jang Min-Soo
Han Sang-Hwa
Kim Joon-Hee
Lee Kang-Hoon
Park Jong-Bin
Kim Sang-Tae
Suh Kee-Suck
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Abstract
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Cutaneous metastases of malignant melanoma are usually confined to the dermis or subcutaneous fat. In someinstances, however, they may involve the epidermis. A 68-year-old woman with a malignant melanoma on thesubungual area of the right great toe presented with multiple blackish pinhead-sized macules surrounding anulcerative lesion on the right great toe. Histopathological study of the macules showed atypical melanocytes andmelanocytic nests in the papillary dermis and the dermoepidermal junction. A thinning of the epidermis, wideningof the dermal papillae by aggregated atypical melanocytes, epidermal collarette formation, and angiotropism werealso seen. A diagnosis of epidermotropic metastatic malignant melanoma (EMMM) was made. EMMM is a specificform of metastatic malignant melanoma that is associated with epidermotropism of melanoma cells and severalhistopathological features. The differential diagnosis between primary malignant melanoma and EMMM can bedifficult because of their similar clinical and histological features. Here, we report a case demonstrating EMMM. (Korean J Dermatol 2015;53(1):53∼57)
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KEYWORD
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Angiotropism , Epidermotropic metastatic malignant melanoma , Epidermotropism
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